Junjiang Fu Selected Research

thymoquinone

6/2022	Thymoquinone upregulates IL17RD in controlling the growth and metastasis of triple negative breast cancer cells in vitro.
3/2022	PIK3CA hotspot mutations p. H1047R and p. H1047L sensitize breast cancer cells to thymoquinone treatment by regulating the PI3K/Akt1 pathway.
1/2022	Cordycepin Inhibits Triple-Negative Breast Cancer Cell Migration and Invasion by Regulating EMT-TFs SLUG, TWIST1, SNAIL1, and ZEB1.
1/2022	Synergistic Role of Thymoquinone on Anticancer Activity of 5-Fluorouracil in Triple Negative Breast Cancer Cells.
1/2021	RNA-Sequencing Reveals Heat Shock 70-kDa Protein 6 (HSPA6) as a Novel Thymoquinone-Upregulated Gene That Inhibits Growth, Migration, and Invasion of Triple-Negative Breast Cancer Cells.
12/2019	Epigenetic role of thymoquinone: impact on cellular mechanism and cancer therapeutics.
12/2017	Thymoquinone Inhibits the Migration and Invasive Characteristics of Cervical Cancer Cells SiHa and CaSki In Vitro by Targeting Epithelial to Mesenchymal Transition Associated Transcription Factors Twist1 and Zeb1.
8/2017	Thymoquinone, as an anticancer molecule: from basic research to clinical investigation.
8/2015	Thymoquinone inhibits cancer metastasis by downregulating TWIST1 expression to reduce epithelial to mesenchymal transition.

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Junjiang Fu Research Topics

Disease

28	Neoplasms (Cancer) 08/2022 - 02/2011
17	Neoplasm Metastasis (Metastasis) 06/2022 - 02/2011
15	Breast Neoplasms (Breast Cancer) 03/2022 - 03/2009
8	Carcinogenesis 01/2022 - 01/2013
6	Cicatrix (Scar) 08/2020 - 01/2013
5	Lung Neoplasms (Lung Cancer) 01/2022 - 01/2019
4	Triple Negative Breast Neoplasms 06/2022 - 01/2021
4	COVID-19 01/2021 - 06/2020
3	Prostatic Neoplasms (Prostate Cancer) 07/2019 - 03/2009
3	Inflammation (Inflammations) 01/2018 - 01/2013
2	Chronic Obstructive Pulmonary Disease (COPD) 01/2021 - 08/2016
2	Retinitis Pigmentosa (Pigmentary Retinopathy) 01/2018 - 01/2015
2	Ductal Carcinoma 07/2017 - 06/2011
1	Liver Neoplasms (Liver Cancer) 08/2022
1	Pathologic Processes 01/2021
1	type 2A Usher syndrome 01/2020
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2019
1	Macular Degeneration (Age-Related Maculopathy) 11/2018
1	Eye Diseases (Eye Disease) 01/2018
1	Colonic Neoplasms (Colon Cancer) 01/2018
1	Colorectal Neoplasms (Colorectal Cancer) 01/2018
1	Colitis-Associated Neoplasms 01/2018
1	Familial Exudative Vitreoretinopathies 01/2018
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 12/2017
1	Genomic Instability 07/2017
1	Choroideremia 03/2017
1	Albuminuria 04/2016

Drug/Important Bio-Agent (IBA)

16	Proteins (Proteins, Gene)FDA Link 01/2022 - 02/2011
9	thymoquinoneIBA 06/2022 - 08/2015
9	DNA (Deoxyribonucleic Acid)IBA 12/2018 - 03/2009
6	Messenger RNA (mRNA)IBA 01/2022 - 08/2016
5	Transcription Factors (Transcription Factor)IBA 01/2022 - 08/2014
4	Biomarkers (Surrogate Marker)IBA 01/2020 - 01/2017
4	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2020 - 01/2013
3	Pharmaceutical PreparationsIBA 08/2022 - 08/2017
3	Protein Isoforms (Isoforms)IBA 01/2022 - 01/2021
3	Peptide Hydrolases (Proteases)FDA Link 01/2022 - 01/2021
3	Histones (Histone)IBA 01/2021 - 01/2012
3	Cadherins (E-Cadherin)IBA 01/2020 - 08/2014
3	Retinaldehyde (Retinal)IBA 11/2018 - 01/2015
3	Twist-Related Protein 1IBA 05/2016 - 06/2011
3	Basic Helix-Loop-Helix Transcription FactorsIBA 05/2016 - 06/2011
2	Biological ProductsIBA 01/2022 - 12/2017
2	FurinIBA 01/2022 - 01/2021
2	cordycepinIBA 01/2022 - 01/2019
2	AndrogensIBA 01/2021 - 08/2017
2	Androgen Receptors (Androgen Receptor)IBA 07/2019 - 03/2009
2	Genetic Markers (Genetic Marker)IBA 07/2017 - 11/2015
2	Serine (L-Serine)FDA Link 05/2016 - 06/2011
1	EnzymesIBA 08/2022
1	Pyruvate KinaseIBA 08/2022
1	Fluorouracil (Carac)FDA LinkGeneric 01/2022
1	VaccinesIBA 01/2022
1	Pattern Recognition ReceptorsIBA 01/2022
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2022
1	Cysteine Proteases (Cysteine Protease)IBA 01/2022
1	Immunologic Factors (Immunomodulators)IBA 01/2022
1	MicroRNAs (MicroRNA)IBA 11/2021
1	3' Untranslated Regions (3' UTR)IBA 11/2021
1	Endoplasmic Reticulum Chaperone BiPIBA 01/2021
1	RNA (Ribonucleic Acid)IBA 01/2021
1	tRNA MethyltransferasesIBA 01/2021
1	TrypsinIBA 01/2021
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2021
1	Retinal DehydrogenaseIBA 01/2021
1	NucleotidesIBA 08/2020
1	Angiotensin-Converting Enzyme 2IBA 06/2020
1	Ubiquitin-Specific ProteasesIBA 07/2019
1	Deubiquitinating EnzymesIBA 07/2019
1	Ubiquitin CIBA 07/2019
1	HydrolasesIBA 07/2019
1	Competitive Endogenous RNAIBA 02/2019
1	ErbB Receptors (EGF Receptor)IBA 01/2019
1	AfatinibIBA 01/2019
1	Gefitinib (Iressa)FDA Link 01/2019
1	GTP Phosphohydrolases (GTPases)IBA 01/2018
1	Oncogene Proteins (Oncogene Protein)IBA 01/2018
1	NF-kappa B (NF-kB)IBA 01/2018
1	enzalutamideIBA 08/2017
1	abirateroneIBA 08/2017
1	ResveratrolIBA 08/2017
1	LigandsIBA 08/2017
1	dichlorobis(azomycin)platinum IIIBA 03/2017
1	Nonsense Codon (Nonsense Mutation)IBA 03/2017
1	Interleukin-17 (Interleukin 17)IBA 08/2016
1	GoldIBA 08/2016
1	CytokinesIBA 08/2016
1	Interleukin-10 (Interleukin 10)IBA 08/2016
1	Mustard Gas (Sulfur Mustard)IBA 08/2016
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 05/2016
1	CreatineIBA 04/2016
1	Triglycerides (Triacylglycerol)IBA 04/2016
1	Blood Glucose (Blood Sugar)IBA 04/2016
1	HDL LipoproteinsIBA 04/2016
1	LipidsIBA 04/2016
1	LDL Lipoproteins (beta Lipoproteins)IBA 04/2016
1	CholesterolIBA 04/2016

Therapy/Procedure

18	Therapeutics 08/2022 - 01/2012
2	Castration 07/2019 - 08/2017
1	Drug Therapy (Chemotherapy) 01/2022